PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Synonyms:
PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K
Species:
Human PIK3CG (5294), Mouse Pik3cg (30955), Rat Pik3cg (298947), Zebrafish pik3cg (406598), Zebrafish pik3cg (564261), chicken PIK3CG (417706), dog PIK3CG (483266), domestic cat PIK3CG (101096215), cow PIK3CG (530001), sheep PIK3CG (101102896) ...More
UniProtKB ID:
Gene ID:
- Human(5294) Summary: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008]
- Mouse(30955) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- Rat(298947) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- Zebrafish(406598) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- Zebrafish(564261) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- chicken(417706) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- dog(483266) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- domestic cat(101096215) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- cow(530001) phosphoinositide-3-kinase, catalytic, gamma polypeptide
- sheep(101102896) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- naked mole-rat(101707055) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
- domestic guinea pig(100725386) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PIK3CG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-PIK3CG antibody produced in mouse, clone 2G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
PI3 kinase (p120g) Active human, recombinant, expressed in baculovirus infected insect cells, ≥90% (SDS-PAGE),
Species
human
Phosphoinositide 3-kinase p110γ human, ≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species