Skip to Content
MilliporeSigma

LRP5

low density lipoprotein receptor-related protein 5

Synonyms:
BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2
Species:
UniProtKB ID:
Gene ID:
  • Human(4041) Summary: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. [provided by RefSeq, Nov 2009]
  • Mouse(16973) low density lipoprotein receptor-related protein 5
  • Rat(293649) low density lipoprotein receptor-related protein 5
  • Zebrafish(568518) low density lipoprotein receptor-related protein 5
  • cow(534450) low density lipoprotein receptor-related protein 5
  • Horse(100147353) low density lipoprotein receptor-related protein 5
  • domestic cat(101084481) low density lipoprotein receptor-related protein 5
  • dog(100306933) low density lipoprotein receptor-related protein 5
  • chicken(423114) low density lipoprotein receptor-related protein 5
  • Domestic Rabbit(100009566) low density lipoprotein receptor-related protein 5
  • naked mole-rat(101711921) low density lipoprotein receptor-related protein 5
  • domestic guinea pig(100714196) low density lipoprotein receptor-related protein 5
  • sheep(101113714) low density lipoprotein receptor-related protein 5

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LRP5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-LRP5 antibody produced in mouse, clone 1E9, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-LRP5 antibody produced in mouse, clone 1E9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Lrp5,
Species
mouse