HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
Synonyms:
SSS2
Species:
Human HCN4 (10021), Mouse Hcn4 (330953), Rat Hcn4 (59266), domestic guinea pig Hcn4 (100717049), naked mole-rat Hcn4 (101715130), sheep HCN4 (101117337), Domestic Rabbit HCN4 (100009452), Zebrafish hcn4 (557843), cow HCN4 (785689), domestic cat HCN4 (101090363) ...More
UniProtKB ID:
Gene ID:
- Human(10021) Summary: This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008]
- Mouse(330953) hyperpolarization-activated, cyclic nucleotide-gated K+ 4
- Rat(59266) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- domestic guinea pig(100717049) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- naked mole-rat(101715130) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- sheep(101117337) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- Domestic Rabbit(100009452) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- Zebrafish(557843) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- cow(785689) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- domestic cat(101090363) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- dog(448794) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
- chicken(427478) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HCN4 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-HCN4 antibody produced in mouse, clone S114-10, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-HCN4, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry