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900862

Sigma-Aldrich

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

Sinónimos:

Hydroxyl diazirine TMS-alkyne, Probe building block

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About This Item

Fórmula empírica (notación de Hill):
C14H15F3N2OSi
Número de CAS:
2187374-13-4
Peso molecular:
312.36
UNSPSC Code:
12352200
NACRES:
NA.22

assay

≥95%

form

powder or crystals

storage temp.

−20°C

SMILES string

OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C

Application

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifunctional Probe Building Blocks

Related product

Referencia del producto
Descripción
Precios

900603

(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900598

(4-(Bromomethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900599

(4-(Aminomethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, 95%

900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid, ≥95%

900601

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900602

4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid, ≥95%

900605

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900615

(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900614

3-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid, ≥95%

900613

5-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)pentanoic acid, ≥95%

900611

(3-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900610

Hydroxyl di-benzophenone (PEG)3 alkyne

900617

(4-(Hydroxymethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900619

4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzaldehyde, ≥95%

900616

3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine, ≥95%

900618

3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3H-diazirine, 95%

900683

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine, 95%

900750

(4-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone HCl salt, ≥95%

900831

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

900848

4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride

900847

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid, ≥95%

900858

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid, ≥95%

900860

3-Amino-5-ethynylbenzenesulfonyl fluoride, ≥95%

900862

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

900859

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900863

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol, ≥95%

900864

4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900865

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

906298

3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine

907308

(3-(1,1-Difluoro-3-(triisopropylsilyl)prop-2-yn-1-yl)-3H-diazirin-3-yl)methanol, ≥95%

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Artículos

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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