900601

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Sinónimos: Formyl sulfonyl fluoride alkyne, Probe building block
• Fórmula empírica (notación de Hill): C₁₂H₁₃FO₃SSi
• Número de CAS: 2088829-13-2
• Peso molecular: 284.38
• UNSPSC Code: 12352200
• NACRES: NA.22

Propiedades

• assay: ≥95%
• form: solid
• reaction suitability: reaction type: click chemistry
• storage temp.: −20°C
• SMILES string: O=C([H])C1=CC(S(=O)(F)=O)=CC(C#C[Si](C)(C)C)=C1

Descripción

Application

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl group, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable