LC/MS (TOF) Analysis of 2C Amine Drugs of Abuse on Ascentis® Express HILIC
CONDITIONS
column
Ascentis Express HILIC, 5 cm x 2.1 mm I.D., 2.7 μm particles (53934-U)
mobile phase
2 mM ammonium formate in 90:10 (v:v) acetonitrile:water
flow rate
0.4 mL/min
pressure
943 psi (65 bar)
column temp.
35 °C
detector
TOF/MS
injection
2 μL
sample
300 ng/mL in acetonitrile
Description
Analysis Note
The 2C amines are a family of illicit, psychedelic phenethylamines. The term "2C" refers to the two carbon atoms between the benzene ring and the amino group in the parent molecular structure. A rapid separation of four 2C amine compounds is shown here on an Ascentis Express HILIC column with TOF-MS detection. Cerilliant CRMs were used to ensure reliable MS identification and quantification.
Legal Information
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany