Nucleosides and Nucleotides

Illustration of the location and structure of DNA double helix highlighting components that hold the gene specificity of every living being.

Nucleosides and nucleotides and their derivatives are biologically ubiquitous substances that participate in nearly all biochemical processes. They form the monomeric units of nucleic acids and thereby play central roles in both the expression and storage of genetic information.

Nucleosides are glycosylamines obtained by chemical or enzymatic decomposition of nucleic acids and contain two components: a five-carbon sugar (ribose or 2’ deoxyribose) and nitrogen base. Examples of nucleosides include adenosine, cytidine, guanosine, and thymidine. They function as signaling molecules and are precursors for nucleotides needed for DNA and RNA synthesis. Nucleosides play an important role in medicine and molecular biology and are used as antiviral or anticancer agents.

As the building block of DNA and RNA, nucleotides are organic molecules composed of three components: a five-carbon sugar, nitrogen base and one or more phosphate groups. Examples of nucleotides include adenine, cytosine, guanine, thymine, and uracil. Nucleotides are not only the basic unit of genetic material in all living things, they also play a role in the energy, metabolism, and signaling in cells.


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Cell Biology and Drug Discorery

We offer a large selection of natural and synthetic nucleosides, nucleotides, oligonucleotides, and their analogs for a multitude of research, diagnostic and manufacturing applications in cell biology and drug discovery. We’re dedicated to supporting your scientific advancement with our innovative and reliable bioreagents available in mg to kg batch sizes to precisely meet your needs.

Breakthroughs feel closer than ever with our unparalleled portfolio:

  • Adenosine-derived nucleosides and nucleotides
  • Metabolic nucleotides
  • Cancer and proliferation biomarker nucleosides
  • Non-hydrolyzable nucleotide analogs
  • Coenzymes and essential cofactors
  • Cell culture, cell-arrest, cell inhibitor nucleosides
  • Protein purification nucleosides
  • Molecular & HPLC standards