1650006

Tetracaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine hydrochloride
• Empirical Formula (Hill Notation): C₁₅H₂₄N₂O₂ · HCl
• CAS Number: 136-47-0
• Molecular Weight: 300.82
• MDL number: MFCD00038912
• UNSPSC Code: 41116107
• PubChem Substance ID: 329751254
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: tetracaine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
• InChI: 1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
• InChI key: PPWHTZKZQNXVAE-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tetracaine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Benzocaine, Butamben, and Tetracaine Hydrochloride Gel
• Benzocaine, Butamben, and Tetracaine Hydrochloride Ointment
• Benzocaine, Butamben, and Tetracaine Hydrochloride Topical Aerosol^®
• Benzocaine, Butamben, and Tetracaine Hydrochloride Topical Solution
• Lidocaine, Racepinephrine, and Tetracaine Hydrochlorides Compounded Topical Gel
• Neomycin Sulfate, Isoflupredone Acetate, and Tetracaine Hydrochloride Ointment
• Neomycin Sulfate, Isoflupredone Acetate, and Tetracaine Hydrochloride Topical Powder

Topical ophthalmic anesthetic; used for spinal anesthesia

Biochem/physiol Actions

Blocks voltage-sensitive release of Ca²⁺ from sarcoplasmic reticulum.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Legal Information

Aerosol is a registered trademark of Cytec Technology Corp.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H319,H336
• pcodes: P261 - P264 - P271 - P280 - P301 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable