1370101

Lopinavir

United States Pharmacopeia (USP) Reference Standard

• Empirical Formula (Hill Notation): C₃₇H₄₈N₄O₅
• CAS Number: 192725-17-0
• Molecular Weight: 628.80
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• biological source: synthetic
• grade: pharmaceutical primary standard
• agency: USP/NF
• API family: lopinavir
• form: powder
• packaging: pkg of 350 mg
• manufacturer/tradename: USP
• storage condition: protect from light
• color: white to off-white
• mp: 255.2-260.6 °F (124—127°C)
• solubility: chloroform: soluble; isopropanol: soluble; methanol: freely soluble; methylene chloride: freely soluble; water: practically insoluble
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• InChI: 1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
• InChI key: KJHKTHWMRKYKJE-SUGCFTRWSA-N

Description

General description

Lopinavir is an antiretroviral agent and a protease inhibitor indicated for the management of human immunodeficiency virus (HIV) infection. It is a key component of Kaletra, the co-formulation of lopinavir and ritonavir.

Application

Lopinavir may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and plasma samples by chromatography techniques.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable