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USP

Imidazole

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1,3-Diaza-2,4-cyclopentadiene, Glyoxaline

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About This Item

Empirical Formula (Hill Notation):
C3H4N2
CAS Number:
288-32-4
Molecular Weight:
68.08
Beilstein/REAXYS Number:
103853
MDL number:
MFCD00005183
UNSPSC Code:
41116107
PubChem Substance ID:
329750151
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor pressure

<1 mmHg ( 20 °C)

API family

imidazole

manufacturer/tradename

USP

pKa (25 °C)

6.95

bp

256 °C (lit.)

mp

88-91 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

InChI key

RAXXELZNTBOGNW-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Imidazole USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard, system suitability, and system suitability stock solution for impurity analysis by using liquid chromatography in conjunction with UV detector in accordance with the given below monographs of United States Pharmacopeia (USP) :
  • Clotrimazole Topical Solution
  • Perindopril Erbumine
  • Moexipril Hydrochloride
  • Clotrimazole Vaginal Inserts
Excellent for buffers in the range of pH 6.2-7.8

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

flash_point_f

293.0 °F - closed cup

flash_point_c

145 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protocols

Sildenafil Citrate USP Method Using HPTLC Plates for the Limit of Imidazole Test

In the present study we demonstrate compliance of silica gel 60 F254 HPTLC plates with USP requirements, and how HPTLC plates are suitable for the Sildenafil citrate-Limit of Imidazole test.

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