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1087508

USP

Camphor

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

D-Camphor, 2-Bornanone, 2-Camphanone

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About This Item

Empirical Formula (Hill Notation):
C10H16O
CAS Number:
464-49-3
Molecular Weight:
152.23
MDL number:
MFCD00064149
UNSPSC Code:
41116107
PubChem Substance ID:
329749215
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

5.24 (vs air)

vapor pressure

4 mmHg ( 70 °C)

API family

methyl benzylidene camphor

autoignition temp.

870 °F

expl. lim.

3.5 %

manufacturer/tradename

USP

mp

178-182 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC1(C)[C@@H]2CC[C@@]1(C)C(=O)C2

InChI

1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1

InChI key

DSSYKIVIOFKYAU-XCBNKYQSSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Camphor USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Camphorated Phenol Topical Gel
  • Camphorated Phenol Topical Solution
  • Eucalyptus Oil

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 2 Inhalation

target_organs

Lungs

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 1

flash_point_f

147.2 °F - closed cup

flash_point_c

64 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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DL-Camphor for synthesis

Sigma-Aldrich

8.41456

DL-Camphor

Menthol United States Pharmacopeia (USP) Reference Standard

USP

1381709

Menthol

Methyl salicylate United States Pharmacopeia (USP) Reference Standard

USP

1437450

Methyl salicylate

D-Camphor ≥97%, FG

Sigma-Aldrich

W223018

D-Camphor

Eucalyptol United States Pharmacopeia (USP) Reference Standard

USP

1268900

Eucalyptol

USP

USP

1268919

Eucalyptus oil

D E Gibson et al.
The American journal of emergency medicine, 7(1), 41-43 (1989-01-01)
Camphor ingestion is a toxic ingestion that is seen infrequently in the emergency department. It is remarkable for its rapidity of action and toxicity. A case of camphor ingestion that displayed toxic effects is presented. The pharmacology, manifestations, and management
Equilibrium states and dynamic reactions of iron in the camphor monoxygenase system.
I C Gunsalus et al.
Advances in experimental medicine and biology, 74, 254-262 (1976-01-01)
Ju-Young Kim et al.
Drug delivery, 21(7), 519-529 (2013-11-20)
The aims of the present study were to prepare new dual-mode floating gastroretentive tablets (DF-GRT) containing itraconazole (ITR) and to evaluate influence of the dosage forms on pharmacokinetic parameters of ITR. The solubility of ITR was enhanced around 200 times
E Siegel et al.
Pediatric clinics of North America, 33(2), 375-379 (1986-04-01)
Camphor is present in several over-the-counter compounds of questionable use and therefore may be ingested by small children. Because seizures may follow ingestion of certain amounts, appropriate treatment is needed, including the use of anticonvulsants.
Jeffrey N Love et al.
The Journal of emergency medicine, 27(1), 49-54 (2004-06-29)
Serious pediatric toxicity resulting from exposure to small amounts of camphor-containing products has long been a problem. Twenty years ago the United States Food and Drug Administration took several actions in an attempt to ameliorate this risk. Despite these changes
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