1036110

Aniline

United States Pharmacopeia (USP) Reference Standard

• Linear Formula: C₆H₅NH₂
• CAS Number: 62-53-3
• Molecular Weight: 93.13
• Beilstein/REAXYS Number: 605631
• MDL number: MFCD00007629
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749034
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• vapor density: 3.22 (185 °C, vs air)
• vapor pressure: 0.7 mmHg ( 25 °C)
• API family: aniline
• autoignition temp.: 1139 °F
• expl. lim.: 11 %
• manufacturer/tradename: USP
• refractive index: n20/D 1.586 (lit.)
• bp: 184 °C (lit.)
• mp: −6 °C (lit.)
• density: 1.022 g/mL at 25 °C (lit.)
• application(s): pharmaceutical
• format: neat
• SMILES string: Nc1ccccc1
• InChI: 1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2
• InChI key: PAYRUJLWNCNPSJ-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aniline USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H301 + H311 + H331,H317,H318,H341,H351,H372,H410
• pcodes: P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1
• target_organs: Blood
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 158.0 °F - closed cup
• flash_point_c: 70 °C - closed cup