Y0002125

Alfacalcidol for system suitability A

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): 1α-Hydroxyvitamin D₃, 1α-Hydroxycholecalciferol, Alfacalcidol
• Empirical Formula (Hill Notation): C₂₇H₄₄O₂
• CAS Number: 41294-56-8
• Molecular Weight: 400.64
• MDL number: MFCD00868328
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• API family: alfacalcidol
• manufacturer/tradename: EDQM
• storage temp.: −20°C
• SMILES string: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C
• InChI: 1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1
• InChI key: OFHCOWSQAMBJIW-AVJTYSNKSA-N
• Gene Information: human ... VDR(7421)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Alfacalcidol for system suitability A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Synthetic vitamin D₃ analog that is metabolized to 1,25-dihydroxycholecalciferol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300
• pcodes: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 1 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable