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Aroclor 1254

ampule of 50 mg, analytical standard

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About This Item

CAS Number:
UNSPSC Code:
12000000

grade

analytical standard

Quality Level

CofA

current certificate can be downloaded

packaging

ampule of 50 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental

format

neat

storage temp.

2-30°C

InChI

1S/C12H5Cl5/c13-8-3-1-2-6(10(8)15)7-4-5-9(14)12(17)11(7)16/h1-5H

InChI key

AUGNBQPSMWGAJE-UHFFFAOYSA-N

General description

Aroclor 1254 is a mixture of several polychlorinated biphenyls, which has been used for chicken embryogenesis and hatching process in order to reduce thyroid hormone levels in blood plasma. It can also work as a powerful inducer of both cytochrome P-448 and P-450 and hence exhibit the catalytic properties of both cytochromes in the liver.

Application

Aroclor 1254 may be used as an analytical standard for the determination of the analyte in pesticide samples and environmental samples by chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Gas chromatograph/mass spectrometer techniques for determination of interferences in pesticide analysis
Bonelli EJ
Analytical Chemistry, 44(3), 603-606 (1972)
Heterogeneity of cytochrome P-450s induced by polychlorinated biphenyls.[Aroclor 1254]
Alvares AP, et al.
The Journal of Biological Chemistry, 252 (1977)
Effect of in ovo injection of Aroclor 1254 on embryonic development, time of hatching, and blood thyroid hormone levels in one-day-old chicken
Lis.WM, et al.
Bulletin of the Veterinary Institute in Pulawy, 55, 293-292 (2011)
Saydur Rahman et al.
Journal of toxicology and environmental health. Part B, Critical reviews, 14(5-7), 473-494 (2011-07-28)
Tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin (5-HT) synthesis, performs an essential role in the maintenance of serotonergic functions in the central nervous system (CNS), including regulation of the neuroendocrine system controlling reproduction. The results of recent studies in
Sylvie Cotelle et al.
Environmental science and pollution research international, 19(3), 628-635 (2011-09-08)
Assessment of environmental impacts from pesticide utilization should include genotoxicity studies, where the possible effects of mutagenic/genotoxic substances on individuals are assessed. In this study, the genotoxicity profile of the new formicide Macex® was evaluated with two genotoxicity tests, namely

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