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20124AST

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Astec® CYCLOBOND I 2000 AC Chiral (5 μm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

Synonym(s):

Cyclodextrin-based Chiral Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Astec® CYCLOBOND I 2000 AC Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

material

stainless steel column

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-50 °C temperature
172 bar pressure (2500 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

25 cm × 4.6 mm

matrix

silica particle platform

matrix active group

cyclodextrin, beta- phase

particle size

5 μm

pore size

100 Å

operating pH

3.5-7

separation technique

chiral

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General description

CYCLOBOND I 2000 AC is used primarily for aromatic alcohols or amines that are chiral on the α or β carbon.

  • Bonded phase: Acetylated beta-cyclodextrin

Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature

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Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

Lot/Batch Number
277150-04
277150-03
277150-02
277150-01
276460-04

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Separation of Beraprost sodium isomers using different cyclodextrin stationary phases
Walker, Thomas A.
Journal of Chromatography A, 633 (1-2), 97-103 (1993)
Optical resolution of flavanones by high-performance liquid chromatography on various chiral stationary phases
Krause, Martin; Galensa, Rodolf
Journal of Chromatography A, 514, 147-159 (1990)
Yasith S Nanayakkara et al.
Journal of chromatography. A, 1305, 94-101 (2013-08-03)
Isochromene derivatives are very important precursors in the natural products industry. Hence the enantiomeric separations of chiral isochromenes are important in the pharmaceutical industry and for organic asymmetric synthesis. Here we report enantiomeric separations of 21 different chiral isochromene derivatives
K H Kim et al.
Archives of pharmacal research, 23(3), 230-236 (2000-07-15)
(1'R, 2R)-, (1'R, 2S)-, (1'S, 2R)- and (1'S, 2S)-alpha-hydroxymetoprolol; (2R)- and (2S)-O-desmethylmetoprolol; and (2R)- and (2S)-metoprolol acid are major metabolites of (2R)-and (2S)-metoprolol, beta-adrenergic antagonist. The focus of most chiral separation methods until now has been on determination of the
Reprint of: Enantiomeric separation of functionalized ethano-bridged Troger bases using macrocyclic cyclofructan and cyclodextrin chiral selectors in high-performance liquid chromatography and capillary electrophoresis with application of principal component analysis
Weatherly, Choyce A., et al.
Journal of Chromatography. B, Biomedical Applications, 968, 40-48 (2014)
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Related Content

Astec CYCLOBOND™

CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.

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