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Key Documents

SRP5242

Sigma-Aldrich

ERK5, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

BMK1, ERK4, MAPK7, PRKM7

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About This Item

CAS Number:
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

9.4-12.7 nmol/min·mg

mol wt

~132 kDa

NCBI accession no.

application(s)

cell analysis

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... MAPK7(5598)

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Identification and validation of dysregulated MAPK7 (ERK5) as a novel oncogenic target in squamous cell lung and esophageal carcinoma
Paul R. Gavine
BMC Cancer (2015)
MAPK7 gene controls proliferation, migration and cell invasion in osteosarcoma.
Tesser-Gamba F
Molecular Carcinogenesis (2016)
C1q-TNF-related protein-9 promotes cardiac hypertrophy and failure
Mahesh Appari
Circulation Research (2016)
ERK5 Mediated Signalling in Diabetic Retinopathy
Yuexiu Wu
Medical Hypotheses (2015)
Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects
Christopher
Proceedings of the National Academy of Sciences of the USA (2002)

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