SRP4210

GRO/KC from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• Synonym(s): CXCL1, GRO α, GRO1, Growth-regulated α protein, NAP-3
• MDL number: MFCD00165726
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: mouse
• recombinant: expressed in E. coli
• assay: ≥98% (HPLC); ≥98% (SDS-PAGE)
• form: lyophilized
• potency: 10-100 ng/mL
• mol wt: ~7.8 kDa
• packaging: pkg of 20 μg
• impurities: endotoxin, tested
• NCBI accession no.: P12850
• UniProt accession no.: P12850
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... Cxcl1(14825)

Description

General description

Growth-regulated oncogenes (GRO)/keratinocyte chemoattractant (KC) belongs to the growing inflammatory protein superfamily. KC is characterized with four conserved cysteine residues with a CXC motif.

Mouse KC (also known as mouse GRO-α) belongs to the C-X-C family of chemokines. Mouse KC is a 7.8 kDa protein containing 72 amino acid residues.

Biochem/physiol Actions

Growth-regulated oncogenes (GRO)/keratinocyte chemoattractant (KC) plays a vital role in wound healing and inflammation. In rat, serum levels of GRO/KC can be used as a predictive biomarker for inhibitory effect of chemopreventive agents on esophageal carcinogenesis.

Physical form

Sterile filtered and then lyophilized without any additives.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1 mg/mL. This solution can be diluted into other aqueous buffers.