SRP0465
BRDT (257-382) His tag human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym(s):
BRD6, CT9, bromodomain, testis-specific
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
General description
Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9 (GenBank Accession No. NM_207189) amino-acids 257 – 382 with N-terminal HIS-tag, MW = 15.8 kDa, expressed in an E. coli expression system.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Enyuan Shang et al.
Development (Cambridge, England), 134(19), 3507-3515 (2007-08-31)
Brdt is a testis-specific member of the distinctive BET sub-family of bromodomain motif-containing proteins, a motif that binds acetylated lysines and is implicated in chromatin remodeling. Its expression is restricted to the germ line, specifically to pachytene and diplotene spermatocytes
Binyamin D Berkovits et al.
Developmental biology, 360(2), 358-368 (2011-10-25)
Mice homozygous for a mutation (Brdt(∆BD1/∆BD1)) lacking the first bromodomain of Brdt, a testis-specific member of the BET family of double-bromodomain containing proteins, are sterile and exhibit profound defects in chromatin remodeling during spermiogenesis. We have now observed that a
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