SRP0442
UEV1A active human
recombinant, expressed in E. coli, ≥80% (SDS-PAGE)
Synonym(s):
CIR1, CROC1, UBE2V1, ubiquitin-conjugating enzyme E2 variant 1
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
biological source
human
recombinant
expressed in E. coli
assay
≥80% (SDS-PAGE)
form
aqueous solution
mol wt
20 kDa
packaging
pkg of 100 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... UBE2V1(7335)
General description
UEV1A (ubiquitin-conjugating enzyme E2 variant 1), also known as UBE2V1 or CROC-1 (GenBank Accession No. NM_021988) amino acids 2-170 (end) with N-terminal FLAG-tag, MW=20 kDa, expressed in E. coli.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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D Duong Hau et al.
Biochemistry, 45(32), 9866-9877 (2006-08-09)
Lys(63)-linked polyubiquitination of TRAF2 or TRAF6 is an essential step within the signal transduction cascade responsible for activation of p38, c-Jun N-terminal kinase, and the transcription factor NF-kappaB. Attachment of ubiquitin (Ub) to a TRAF, and conjugation of Ub molecules
T M Thomson et al.
FEBS letters, 423(1), 49-52 (1998-05-15)
The open reading frame YGL087c in the budding yeast Saccharomyces cerevisiae genome encodes a polypeptide highly similar to the human UEV (ubiquitin-conjugating E2 enzyme variant) proteins, which have been proposed to belong to a family of putative dominant negative ubiquitin
L Ma et al.
Oncogene, 17(10), 1321-1326 (1998-10-15)
Acquisition of the immortal phenotype by tumor cells represents an essential and potentially rate-limiting step in tumorigenesis. To identify changes in gene expression that are associated with the early stages of cell immortalization, we compared genetically matched pairs of pre-immortal
Jing Geng et al.
Nature immunology, 16(11), 1142-1152 (2015-09-29)
Mitochondria need to be juxtaposed to phagosomes for the synergistic production of ample reactive oxygen species (ROS) in phagocytes to kill pathogens. However, how phagosomes transmit signals to recruit mitochondria has remained unclear. Here we found that the kinases Mst1
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