SML3364

Emodepside

≥95% (HPLC)

• Synonym(s): Bay-44-4400, Cyclo[(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl], PF 1022-221
• Empirical Formula (Hill Notation): C₆₀H₉₀N₆O₁₄
• CAS Number: 155030-63-0
• Molecular Weight: 1119.39
• UNSPSC Code: 51111800
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to off-white
• storage temp.: −20°C
• SMILES string: N5(CCOCC5)c1ccc(cc1)C[C@H]2OC(=O)[C@@H](N(C(=O)[C@H](OC(=O)[C@@H](N(C(=O)[C@H](OC(=O)[C@@H](N(C(=O)[C@H](OC(=O)[C@@H](N(C2=O)C)CC(C)C)C)C)CC(C)C)Cc3ccc(cc3)N4CCOCC4)C)CC(C)C)C)C)CC(C)C
• InChI: 1S/C60H90N6O14/c1-37(2)31-47-57(71)77-41(9)53(67)61(11)50(34-40(7)8)60(74)80-52(36-44-17-21-46(22-18-44)66-25-29-76-30-26-66)56(70)64(14)48(32-38(3)4)58(72)78-42(10)54(68)62(12)49(33-39(5)6)59(73)79-51(55(69)63(47)13)35-43-15-19-45(20-16-43)65-23-27-75-28-24-65/h15-22,37-42,47-52H,23-36H2,1-14H3/t41-,42-,47+,48+,49+,50+,51-,52-/m1/s1
• InChI key: ZMQMTKVVAMWKNY-YSXLEBCMSA-N

Description

Biochem/physiol Actions

Cyclooctadepsipeptide anthelmintic

Emodepside is a cyclooctadepsipeptide anthelmintic a novel mode of action involving the calcium-gated potassium channel SLO-1 in C. elegans, sometimes mediated by a latrophilin (LAT) receptor.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361fd,H373
• pcodes: P202 - P260 - P264 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2 - STOT RE 2
• target_organs: Pancreas,Adrenal gland
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable