SML2712
ES9-17
≥98% (HPLC)
Synonym(s):
5-Bromo-2-thiophenesulfonanilide, 5-Bromo-N-phenyl-2-thiophenesulfonamide
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C10H8BrNO2S2
CAS Number:
Molecular Weight:
318.21
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
O=S(NC1=CC=CC=C1)(C2=CC=C(S2)Br)=O
InChI key
AIZXCKZVUXCHAP-UHFFFAOYSA-N
Biochem/physiol Actions
ES9-17 is a potent and selective inhibitor of clathrin-mediated endocytosis (CME) that binds to N-terminal domain of clathrin heavy chain. ES9-17 inhibits uptake of different endocytic cargoes in Arabidopsis and HeLa cells.
potent and selective inhibitor of clathrin-mediated endocytosis (CME)
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.
If you need assistance, please contact Customer Support.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Wim Dejonghe et al.
Nature chemical biology, 15(6), 641-649 (2019-04-24)
Clathrin-mediated endocytosis (CME) is a highly conserved and essential cellular process in eukaryotic cells, but its dynamic and vital nature makes it challenging to study using classical genetics tools. In contrast, although small molecules can acutely and reversibly perturb CME
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service