Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SML1998

Sigma-Aldrich

KLH45

≥98% (HPLC)

Synonym(s):

N-Cyclohexyl-N-phenethyl-4-(4-(trifluoromethoxy)phenyl)-2H-1,2,3-triazole-2-carboxamide

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C24H25F3N4O2
CAS Number:
Molecular Weight:
458.48
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

assay

≥98% (HPLC)

form

oil

color

colorless to light yellow

storage temp.

2-8°C

SMILES string

O=C(N(CCC1=CC=CC=C1)C2CCCCC2)N(N=C3)N=C3C4=CC=C(OC(F)(F)F)C=C4

Biochem/physiol Actions

KLH45 is an in vivo-active, potent and selective irreversible inhibitor of DDHD2. KLH45 inactivates brain levels of DDHD2 and increases levels of triglycerides in mouse brain.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jordon M Inloes et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(41), 14924-14929 (2014-10-01)
Complex hereditary spastic paraplegia (HSP) is a genetic disorder that causes lower limb spasticity and weakness and intellectual disability. Deleterious mutations in the poorly characterized serine hydrolase DDHD2 are a causative basis for recessive complex HSP. DDHD2 exhibits phospholipase activity

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service