Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SML0638

Sigma-Aldrich

S0859

≥98% (HPLC)

Synonym(s):

2-Chloro-N-[[2′-[(cyanoamino)sulfonyl][1,1′-biphenyl]-4-yl]methyl]-N-[(4-methylphenyl)methyl]-benzamide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C29H24ClN3O3S
CAS Number:
1019331-10-2
Molecular Weight:
530.04
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C29H24ClN3O3S/c1-21-10-12-22(13-11-21)18-33(29(34)26-7-2-4-8-27(26)30)19-23-14-16-24(17-15-23)25-6-3-5-9-28(25)37(35,36)32-20-31/h2-17,32H,18-19H2,1H3

InChI key

ITDBPOSLOROLMT-UHFFFAOYSA-N

Biochem/physiol Actions

S0859 helps to prevent the depolarization-induced alkalinization (DIA) in astrocytes.
S0859 is a selective high-affinity generic inhibitor of the Na+/HCO3- sodium bicarbonate co-transporter (NBC). S0859 does not inhibit Na+-H+ exchange (NHE).

hcodes

H413

Hazard Classifications

Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Adenosine 5′-triphosphate disodium salt hydrate microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)

Sigma-Aldrich

A6419

Adenosine 5′-triphosphate disodium salt hydrate

The Na+/HCO3? co-transporter is protective during ischemia in astrocytes.
Yao H, et al.
Neuroscience, 339, 329-337 (2016)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service