SML0282
Bexarotene
≥98% (HPLC)
Synonym(s):
4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid, LGD-1069, SR-11247
About This Item
Recommended Products
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: ≥15 mg/mL (warmed)
storage temp.
−20°C
SMILES string
C=C(C1=CC=C(C(O)=O)C=C1)C2=C(C)C=C3C(C(C)(C)CCC3(C)C)=C2
InChI
1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)
InChI key
NAVMQTYZDKMPEU-UHFFFAOYSA-N
Gene Information
human ... RXRA(6256) , RXRB(6257) , RXRG(6258)
Application
- to study its effect on human oral squamous cell carcinoma (OSCC) cell lines
- to test for cooperative cell killing of cutaneous T cell lymphoma (CTCL) with 966
- as a standard in HPLC for determining its potential impurities in drug substances and drug products
- to investigate its effects on the changes in renal, cardiac, hepatic, and pulmonary expression/activity of inducible nitric oxide synthase (iNOS) and CYP4F6
- to analyze the involvement of retinoid x receptor (RXR) homo or permissive heterodimers
- to study its potential impurities in drug substances and drug products
Biochem/physiol Actions
Features and Benefits
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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