SMB00428

Resibufogenin

≥98% (HPLC)

• Synonym(s): 14,15-β-epoxy-3-β-hydroxy-5-β-bufa-20,22-dienolide, Bufogenin, RBG, Recibufogenin, Respigon
• Empirical Formula (Hill Notation): C₂₄H₃₂O₄
• CAS Number: 465-39-4
• Molecular Weight: 384.51
• MDL number: MFCD00210361
• UNSPSC Code: 12352205
• PubChem Substance ID: 329825011
• NACRES: NA.25

Properties

• Quality Level: 200
• assay: ≥98% (HPLC)
• form: powder
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: C[C@@]12[C@@]3(O[C@@H]3C[C@@H]2C4=COC(C=C4)=O)[C@]5([H])CC[C@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC1
• InChI: 1S/C24H32O4/c1-22-9-7-16(25)11-15(22)4-5-18-17(22)8-10-23(2)19(12-20-24(18,23)28-20)14-3-6-21(26)27-13-14/h3,6,13,15-20,25H,4-5,7-12H2,1-2H3/t15-,16+,17+,18-,19-,20-,22+,23-,24-/m1/s1
• InChI key: ATLJNLYIJOCWJE-CWMZOUAVSA-N

Description

General description

Resibufogenin is isolated from the skin venom of the Asiatic toad (Bufo gargarizans) known as Chan su in Traditional Chinese Medicine.

Biochem/physiol Actions

Resibufogenin is a specific sodium/potassium-ATPase protein (Na⁺/K⁺-ATPase) inhibitor.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H310 + H330
• pcodes: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable