SBR00037
Solithromycin
≥98% (HPLC)
Synonym(s):
2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, CEM-101, OP-1068
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About This Item
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Quality Level
assay
≥98% (HPLC)
form
powder
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mode of action
protein synthesis | interferes
storage temp.
−20°C
General description
Solithromycin is a highly potent next-generation macrolid. the first fluoroketolid. which has potent activity against most macrolide-resistant strains. Solithromycin (CEM-101) is a novel fluoroketolide with improved antimicrobial effectiveness.
Application
Solithromycin has been shown to have potentent activity against S. pneumoniae as well as an extended spectrum of activity against CA-MRS. enterococc according to in vitro and in vivo research. Solithromycin has been used in:
- the research on the anti-inflammatory effects of macrolides
- the research of potency of solithromycin in comparison to other antimicrobials
- in ithe research of the vitro activity of solithromycin against clinical N. gonorrhoeae isolates and reference strain
Biochem/physiol Actions
Mode of Action: Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis. Like other ketolide. it should impair bacterial ribosomal subunit formation.
Antimicrobial spectrum: Active against bacteria like Legionella, Chlamydophila, Chlamydia, Mycoplasma, and Ureaplasma and against gonococci and other organisms that cause genitourinary tract infections
Antimicrobial spectrum: Active against bacteria like Legionella, Chlamydophila, Chlamydia, Mycoplasma, and Ureaplasma and against gonococci and other organisms that cause genitourinary tract infections
Features and Benefits
High quality antibiotic suitable for mulitple research applications
Other Notes
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Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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