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Key Documents

SAE0149

Sigma-Aldrich

Artificial Saliva for Pharmaceutical Research

Synonym(s):

Artificial Saliva Solution, Saliva Substitute

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About This Item

UNSPSC Code:
51241229
NACRES:
NA.25

shipped in

wet ice

storage temp.

2-8°C

General description

Artificial saliva helps in gaining a stable environment and standardized procedures for in vitro and in vivo studies in pharmacological and bioengineering fields. This saliva mimics the properties of natural saliva in terms of chemical composition and physical characteristics. Artificial Saliva is formulated according to literature for pharmaceutical research such as studies of drug dissolution and drug delivery through the oral mucosa.

Application

Artificial Saliva for pharmaceutical research has been used:

  • to study the antifungal activity of Candida albicans on the surface of printed denture resin discs
  • as a diluting agent for inactivation of Escherichia coli in droplets are with different ambient humidities
  • to determine the stability of graphene oxide-amoxicillin (GO-AMOX) capsules

Components

Sodium Chloride
Potassium Phosphate Monobasic
Potassium Chloride
Potassium Thiocyanate Urea

Storage and Stability

This is a ready to use formulation that should be stored refrigerated.

Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J J Pytko-Polonczyk et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 68(6), 807-813 (2018-03-20)
Examination of dental materials and their properties at the initial stage of the digestive process requires the development of conditions that mimic the environment of the oral cavity. One of the main components of this area is saliva, where many
Anna Trusek et al.
Materials (Basel, Switzerland), 14(12) (2021-07-03)
Graphene oxide (GO) was proposed as an efficient carrier of antibiotics. The model drug, amoxicillin (AMOX), was attached to GO using a peptide linker (Leu-Leu-Gly). GO-AMOX was dispersed in a hydrogel to which the enzyme responsible for releasing AMOX from

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