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Key Documents

SAB5702927

Sigma-Aldrich

Anti-CC2D1A Antibody, clone 5Y6S6, Rabbit Monoclonal

Synonym(s):

CC2D1A, FREUD-1, Freud-1/Aki1, MRT3, coiled-coil and C2 domain containing 1A

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

material

colorless

clone

5Y6S6, monoclonal

form

liquid

mol wt

130 kDa

species reactivity

rat, rat, human

concentration

1.50 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

VLGTAQLKLDALEIACEVREILEVLDGRRPTGGRLEVMVRIREPLTAQQLETTTERWLVIDPVPAAVPTQVAGPKGKAPPVPAPARESGNRSARPLHSLSVLAFDQERLERKILALRQARRPVPPEVAQQYQDIMQRSQWQRAQLEQGGVGIRREYAAQLERQLQFYTEAARRLGNDGSRDAAKEALYRRNLVESELQRLRR

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CC2D1A(54862)

General description

This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5′-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.

Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 750-951 of human CC2D1A (Q6P1N0).

Application

WB, IHC

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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