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Key Documents

SAB4502977

Sigma-Aldrich

Anti-KITH, C-Terminal antibody produced in rabbit

affinity isolated antibody

Synonym(s):

KITH, TK-1, TK1, Thymidine kinase, cytosolic

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 25 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000
western blot: 1:500-1:1000

NCBI accession no.

P04183

UniProt accession no.

P04183

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TK1(7083)

General description

Anti-KITH Antibody detects endogenous levels of total KITH protein.
The Thymidine kinase 1 (TK1) gene is mapped to human chromosome 17q25.3.

Immunogen

The antiserum was produced against synthesized peptide derived from human KITH.

Immunogen Range: 161-210

Biochem/physiol Actions

Thymidine kinase 1 (TK1) takes part in the process of DNA synthesis. It catalyzes the formation of pyrimidine deoxynucleotides through salvage pathway. The enzyme is an ATP dependent kinase. TK1 serves as a biomarker, indicating the recurrence of tumor and metastasis of cancer including gastrointestinal cancer, leukemia and lymphoma.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Expression and Clinical Significance of Cytokeratin-19 and Thymidine Kinase-1 in Advanced Gastrointestinal Cancer.
Du YY
Chinese Medical Journal (English Edition), 129(18), 2168-2172 (2016)
Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer.
D'Costa Z
Cancer Research, 77(21), 5952-5962 (2017)
Fusion of a novel gene, RCC17, to the TFE3 gene in t(X;17)(p11.2;q25.3)-bearing papillary renal cell carcinomas.
Heimann P
Cancer Research, 61(10), 4130-4135 (2001)

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