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Key Documents

SAB4300097

Sigma-Aldrich

Anti-phospho-CDC25C (pSer216) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-CDC25 antibody produced in rabbit, Anti-cell division cycle 25 homolog C (S. pombe) antibody produced in rabbit

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About This Item

MDL number:
MFCD00802890
UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~60 kDa

species reactivity

human

concentration

1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200

isotype

IgG

immunogen sequence

(S-P-SP-M-P)

NCBI accession no.

NP_001781.2

UniProt accession no.

P30307

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer216)

Gene Information

human ... CDC25C(995)

Immunogen

Peptide sequence around phosphorylation site of serine 216 (S-P-S(p)-M-P), according to the protein CDC25C.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclinB-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiplealternatively spliced transcript variants of this gene have been described, however, the full-length nature of many ofthem is not known.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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