SAB3501256

Anti-Swine H1N1 Nucleocapsid Protein antibody produced in rabbit

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: Influenza A virus subtype H1N1 (swine)
• concentration: 1 mg/mL
• technique(s): immunofluorescence: suitable
• isotype: IgG
• UniProt accession no.: C4AL25
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified

Description

General description

Swine H1N1 Nucleocapsid Protein Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. The influenza A virus polymerase transcribes and replicates eight virion RNA (vRNA) segments, among which the nucleocapsid protein (NP), thought to control whether mRNA or cRNA is produced. The nucleoprotein (NP), which has multiple functions during the virus life cycle, possesses regions that are highly conserved among influenza A, B, and C viruses. It was recently found several NP mutations that affected the efficient incorporation of multiple viral-RNA (vRNA) segments into progeny virions even though a single vRNA segment was incorporated efficiently. This indicates that the respective conserved amino acids in NP may be critical for the assembly and/or incorporation of sets of eight vRNA segments.

Immunogen

NP antibody was raised against a synthetic peptide from the swine-Origin H1N1 NP protein.The immunogen is located within amino acids 350 - 400 of Swine H1N1 Nucleocapsid Protein.

Application

NP antibody can be used for the detection of the NP protein from the H1N1 strain of swine-origin Influenza A in ELISA. For immunofluorescence start at 20 μg/mL.

Physical form

Supplied in PBS containing 0.02% sodium azide.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable