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Key Documents

SAB1405504

Sigma-Aldrich

Anti-AZGP1, (C-terminal) antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Synonym(s):

ZA2G, ZAG

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~30.58 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... AZGP1(563)

Immunogen

AZGP1 (AAH33830, 22 a.a. ~ 298 a.a) full-length human protein.

Sequence
ENQGGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKSQPMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVGPWEAS

Application

Anti-AZGP1, (C-terminal) antibody produced in mouse is suitable for western blot.

Biochem/physiol Actions

AZGP1 (α-2-glycoprotein 1, zinc-binding) is a soluble, truncated secretory major histocompatibility complex-related protein involved in lipid degradation. It has structural homology with the class I major histocompatibility complex (MHC) heavy chain. It possesses molecular weight of 38,500 Mr. It consists of a large groove analogous to class I MHC peptide binding grooves. It has been suggested that AZGP1 may be involved in the expression of the immune response.

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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T Araki et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(3), 679-683 (1988-02-01)
In the present study the complete amino acid sequence of human plasma Zn-alpha 2-glycoprotein was determined. This protein whose biological function is unknown consists of a single polypeptide chain of 276 amino acid residues including 8 tryptophan residues and has
L M Sánchez et al.
Science (New York, N.Y.), 283(5409), 1914-1919 (1999-04-17)
Zn-alpha2-glycoprotein (ZAG) is a soluble protein that is present in serum and other body fluids. ZAG stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. The 2.8 angstrom crystal structure of ZAG resembles

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