S5261

Sodium selenite

BioReagent, suitable for cell culture, ≥98%

• Synonym(s): Selenious acid, Sodium salt
• Linear Formula: Na₂SeO₃
• CAS Number: 10102-18-8
• Molecular Weight: 172.94
• EC Number: 233-267-9
• MDL number: MFCD00003489
• PubChem Substance ID: 24899643
• NACRES: NA.75

Properties

• biological source: synthetic (inorganic)
• Quality Level: 200
• product line: BioReagent
• assay: ≥98%
• form: powder
• technique(s): cell culture | mammalian: suitable
• mp: >350 °C (lit.)
• solubility: water: 50 mg/mL, clear to very slightly hazy, colorless
• SMILES string: [Na+].[Na+].[O-][Se]([O-])=O
• InChI: 1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
• InChI key: BVTBRVFYZUCAKH-UHFFFAOYSA-L

Description

Application

Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.

This product is cell culture tested (0.005 mg/L) and is appropriate for use in cell culture applications.[10][11]

Packaging

10, 25, 100 g in glass bottle

Safety Information

• Pictograms: GHS06,GHS09
• Signal Word: Danger
• Hazard Statements: H300 + H330 - H315 - H317 - H319 - H411
• Precautionary Statements: P260 - P273 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Supplementary Hazards: EUH031
• Storage Class Code: 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves