S1314

Monoclonal Anti-SERCa2 ATPase antibody produced in mouse

clone 2A7-A1, ascites fluid

• Synonym(s): Anti-ATP2B, Anti-DAR, Anti-DD, Anti-SERCA2
• MDL number: MFCD00802883
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 200
• conjugate: unconjugated
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: 2A7-A1, monoclonal
• mol wt: antigen 110 kDa
• contains: 0.05% sodium azide
• species reactivity: guinea pig, human, canine, mouse, rat, rabbit
• technique(s): immunoprecipitation (IP): suitable; western blot: suitable
• UniProt accession no.: P16615
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ATP2A2(488) ; mouse ... Atp2a2(11938) ; rat ... Atp2a2(29693)

Description

General description

SERCa2 ATPase (sarco/endoplasmic reticulum calcium-ATPase 2) is also known as ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2). It codes for SERCA2a and SERCA2b, that are expressed in all tissues. SERCA2a is highly expressed in heart. SERCa2 is located on human chromosome 12q24.1.

Immunogen

canine cardiac sarcoplasmic reticulum vesicles

Application

Anti-SERCa2 ATPase antibody has been used in western blotting and immunocytochemistry.

Biochem/physiol Actions

Mutation of SERCa2 ATPase (sarco/endoplasmic reticulum calcium-ATPase 2) or ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca²⁺ transporting 2) causes Dyskeratosis follicularis. SERCA2a plays a major role in controlling cardiomyocyte Ca²⁺. ATP2A2 mutation may cause Darier disease (DD).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable