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RAB0021

Sigma-Aldrich

Human Axl ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum
sample type urine
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 2.74-2000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... AXL(558)

General description

The Human Axl ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Axl in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human Axl

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

AXL receptor tyrosine kinase (AXL) is a receptor for growth arrest-specific protein 6 (GAS6). Along with GAS6, it is involved in the GAS6/AXL signaling pathway which has a role in the acidification-mediated anti-apoptotic effect on endothelial cells. AXL also has a role in interleukin-15-induced human natural killer development from CD34+ hematopoietic progenitor cells (HPCs). This protein is upregulated in several cancers.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Acidification Prevents Endothelial Cell Apoptosis by Axl Activation
Daniela D?Arcangelo
Circulation Research (2002)
Giving AXL the axe: targeting AXL in human malignancy.
Gay CM
British Journal of Cancer (2017)
The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development.
Park IK
Blood (2009)

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