Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

More Documents

R1658

Sigma-Aldrich

RS-102221 hydrochloride hydrate

≥98% (HPLC)

Synonym(s):

4-dione hydrochloride hydrate, 8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulphonam ido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C27H31F3N4O7S·HCl · xH2O
CAS Number:
185376-97-0
Molecular Weight:
649.08 (anhydrous basis)
MDL number:
MFCD18452853
UNSPSC Code:
12352202
PubChem Substance ID:
329824005

assay

≥98% (HPLC)

form

powder

color

white

solubility

DMSO: ≥20 mg/mL

storage temp.

2-8°C

SMILES string

O.Cl.COc1cc(OC)c(cc1NS(=O)(=O)c2ccc(cc2)C(F)(F)F)C(=O)CCCCN3CCC4(CC3)NC(=O)NC4=O

InChI

1S/C27H31F3N4O7S.ClH.H2O/c1-40-22-16-23(41-2)20(33-42(38,39)18-8-6-17(7-9-18)27(28,29)30)15-19(22)21(35)5-3-4-12-34-13-10-26(11-14-34)24(36)31-25(37)32-26;;/h6-9,15-16,33H,3-5,10-14H2,1-2H3,(H2,31,32,36,37);1H;1H2

InChI key

IGACJTZTAQBWKN-UHFFFAOYSA-N

Biochem/physiol Actions

RS-102221 is a selective, high affinity 5-HT2C receptor antagonist.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chris M Panzini et al.
Journal of neurochemistry, 143(6), 708-721 (2017-09-28)
In humans a chromosomal hemideletion of the 16p11.2 region results in variable neurodevelopmental deficits including developmental delay, intellectual disability, and features of autism spectrum disorder (ASD). Serotonin is implicated in ASD but its role remains enigmatic. In this study we

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service