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Application
ProteoPrep® Blue Albumin & IgG Depletion Kit has been used:
- to deplete serum samples from immunoglobulin (Ig) G and albumin
- for albumin removal
- for albumin and IgG removal
- to deplete abundant plasma proteins for two-dimensional electrophoresis
Biochem/physiol Actions
ProteoPrep blue albumin depletion kit is designed to specifically remove albumin and IgG from 25 samples of human serum (25μL to 100μL) in preparation for two-dimensional electrophoresis (2DE). Albumin-depleted serum samples generated by this kit are in urea rather than salt-based buffers with little dilution, eliminating the need to precipitate the sample prior to performing 2DE.
Legal Information
ProteoPrep is a registered trademark of Merck KGaA, Darmstadt, Germany
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Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 3 - Repr. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
Storage Class
3 - Flammable liquids
Certificates of Analysis (COA)
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Qiankun Zhu et al.
Journal of cellular and molecular medicine, 22(1), 533-545 (2017-09-26)
Congenital scoliosis (CS) is a three-dimensional deformity of the spine affecting quality of life. We have demonstrated TBX6 haploinsufficiency is the most important contributor to CS. However, the pathophysiology at the protein level remains unclear. Therefore, this study was to
Angela Baralla et al.
Proteomics. Clinical applications, 12(3), e1700088-e1700088 (2018-02-08)
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation and abnormal inflammatory response of the lungs to inhaled noxious particles or gases. We used a proteomic approach with 2-DE followed by MALDI TOF-MS analyses in order to identify
Bin Liu et al.
Proteome science, 9(1), 24-24 (2011-05-11)
High abundance protein depletion is a major challenge in the study of serum/plasma proteomics. Prior to this study, most commercially available kits for depletion of highly abundant proteins had only been tested and evaluated in adult serum/plasma, while the depletion
Dandan Li et al.
Oncology letters, 18(3), 3349-3357 (2019-08-28)
The serum lipid profile and clinical outcomes of cancer patients are commonly correlated in a wide range of carcinomas. However, few studies have investigated the serum lipid profile of patients with thyroid cancer (TC). The present study therefore aimed to
Karen de Morais-Zani et al.
Journal of biomolecular techniques : JBT, 22(2), 67-73 (2011-07-09)
The proteomic analysis of plasma samples represents a challenge as a result of the presence of highly abundant proteins such as albumin. To enable the detection of biomarkers, which are commonly low-abundance proteins, in complex blood fluids, it is necessary
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