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P7244

Sigma-Aldrich

Poly(Glu, Tyr) sodium salt

greener alternative

Glu:Tyr (4:1), mol wt 5,000-20,000

Synonym(s):

L-Glutamic acid sodium salt (1:1) polymer with L-tyrosine

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.26

form

powder

feed ratio

Glu:Tyr (4:1)

mol wt

5,000-20,000

greener alternative product score

old score: 48
new score: 41
Find out more about DOZN™ Scoring

greener alternative product characteristics

Designing Safer Chemicals
Safer Solvents and Auxiliaries
Reduce Derivatives
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

greener alternative category

storage temp.

−20°C

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Designing Safer Chemicals”, "Safer Solvents and Auxiliaries" and “Reduce Derivatives”. Click here to view its DOZN scorecard.

Analysis Note

Molecular weight based on MALLS.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Soha R Abd El Hadi et al.
Archiv der Pharmazie, 349(11), 827-847 (2016-11-03)
Dual inhibition of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER-2) is an attractive cancer therapeutic approach. In this study, new series of 4-anilinothieno[2,3-d]pyrimidines were designed, synthesized, and tested as dual EGFR/HER-2 kinase
D M Williams et al.
The Journal of biological chemistry, 275(49), 38127-38130 (2000-09-28)
Protein-tyrosine kinases contain a catalytic loop Arg residue located either two or four positions downstream of a highly conserved Asp residue. In this study, the role of this Arg (Arg-318) in the protein-tyrosine kinase C-terminal Src kinase (Csk) was investigated.
Edit Varkondi et al.
Journal of receptor and signal transduction research, 25(1), 45-56 (2005-06-18)
Receptor tyrosine kinases (PTKs) play key roles in the pathogenesis of numerous human diseases, including cancer, and therefore PTK inhibitors are currently under intense investigation as potential drug candidates. PTK inhibitor screening data are, however, poorly comparable because of the
Mohammed K Abd El Hameid et al.
Bioorganic chemistry, 86, 609-623 (2019-02-27)
The work representing the design and the cytotoxic screening of synthetic small molecules (SSMs) such as carbonitriles 3a-c, carboximidamides 4a-c, and oxadiazoles 5-19 as antitumor molecules. Molecules 4c, 9, 12, and 14 show promising cytotoxicity profiles against two cell lines
J Shao et al.
Diabetes, 49(4), 603-610 (2000-06-28)
The cellular mechanisms for the insulin resistance of pregnancy and gestational diabetes mellitus (GDM) are unknown. The membrane protein plasma cell membrane glycoprotein-1 (PC-1) has been identified as an inhibitor of insulin receptor tyrosine kinase (IRTK) activity. We investigated insulin

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