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P3921

Sigma-Aldrich

Parathyroid Hormone Fragment 1-34 rat

≥97% (HPLC), powder

Empirical Formula (Hill Notation):
C180H291N55O48S2
CAS Number:
Molecular Weight:
4057.71
MDL number:
NACRES:
NA.32

Quality Level

assay

≥97% (HPLC)

form

powder

UniProt accession no.

storage temp.

−20°C

Gene Information

rat ... Pth(24694)

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Amino Acid Sequence

Ala-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-leu-Ala-Ser-Val-Glu-Arg-Met-Gln-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe

Application

Parathyroid Hormone Fragment 1-34 rat has been used to study the in vivo effect of parathyroid hormone (PTH) on the intestinal HCO3-secretion in rats. It has also been injected into rats to increase PTH levels and study its effect on the high-phosphate diet-induced elevation of blood pressure.

Biochem/physiol Actions

Parathyroid Hormone Fragment 1-34 is a parathyroid hormone (PTH) analog. It is implicated in the stimulation of intracellular cAMP accumulation and it induces osteocalcin (OC) promoter activity.

Other Notes

Lyophilized from 0.1% TFA in H2O

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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