O0250

(±)-Octopamine hydrochloride

≥95%, solid

• Synonym(s): α-(Aminomethyl)-4-hydroxybenzyl alcohol hydrochloride, (±)-1-(4-Hydroxyphenyl)-2-amino­ethanol hydrochloride
• Linear Formula: HOC₆H₄CH(CH₂NH₂)OH · HCl
• CAS Number: 770-05-8
• Molecular Weight: 189.64
• Beilstein/REAXYS Number: 3915414
• EC Number: 212-216-4
• MDL number: MFCD00012881
• UNSPSC Code: 12352116
• PubChem Substance ID: 24277791
• NACRES: NA.32

Properties

• assay: ≥95%
• form: solid
• color: white to off-white
• mp: ~170 °C (dec.) (lit.)
• solubility: H₂O: soluble
• SMILES string: Cl[H].NCC(O)c1ccc(O)cc1
• InChI: 1S/C8H11NO2.ClH/c9-5-8(11)6-1-3-7(10)4-2-6;/h1-4,8,10-11H,5,9H2;1H
• InChI key: PUMZXCBVHLCWQG-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Description

General description

Octopamine is a biogenic amine, which functions as a neurotransmitter, neuromodulator and neurohormone. It is used to regulate various behaviors, such as learning, memory and aggression. Octopamine is present in mammalian tissues, human urine and invertebrates.

Application

(±)-Octopamine hydrochloride has been used:

• for neurotransmitter assays
• to rupture the encased oocyte into the oviduct
• to specifically induce dramatic assembly of reflectin
• to identify central octopamine receptor-expressing neurons (OARNs) involved in aggression in Drosophila

Biochem/physiol Actions

α-adrenoceptor agonist; invertebrate neurotransmitter.

Caution

hygroscopic - handle under Argon

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319,H412
• pcodes: P264 - P273 - P280 - P305 + P351 + P338 - P337 + P313 - P501
• Hazard Classifications: Aquatic Chronic 3 - Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves