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β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate

≥97% (HPLC)

β-NADPH, Coenzyme II reduced tetrasodium salt, 2′-NADPH hydrate, Triphosphopyridine nucleotide reduced tetrasodium salt, NADPH Na4, TPNH2 Na4, Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt
Empirical Formula (Hill Notation):
C21H26N7Na4O17P3 · xH2O
CAS Number:
Molecular Weight:
833.35 (anhydrous basis)
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


≥97% (HPLC)
≥97% (spectrophotometric assay)




10 mM NaOH: soluble 50 mg/mL, clear

storage temp.


SMILES string




InChI key


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25, 100, 250, 500 mg in poly bottle
1 g in poly bottle

Biochem/physiol Actions

NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects against reactive oxidation species accumulation. NADPH is generated in vivo by the pentose phosphate pathway (PPP).

Preparation Note

Chemically reduced

Other Notes

Packaged based on solid weight.

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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