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Key Documents

MSST0060

Sigma-Aldrich

SILuLite CST3, Cystatin C human

recombinant, expressed in E. coli, MS Protein Standard

Synonym(s):

CST3, Cystatin C

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About This Item

UNSPSC Code:
23201100
NACRES:
NA.32

recombinant

expressed in E. coli

Quality Level

assay

≥95% (SDS-PAGE)

form

lyophilized powder

suitability

suitable for mass spectrometry (internal calibrator)

UniProt accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... CST3(1471)

General description

SILuLite CST3 is a recombinant human protein expressed in E. coli. It consists of 120 amino acids, with a calculated molecular mass of 13.5 kDa. SILuLite CST3 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.

Biochem/physiol Actions

Cystatin C is an inhibitor of cysteine proteases including cathepsin B (which has been identified as the most important ?-amyloid-degrading enzyme. Measurement of cystatin C in serum is replacing creatinine as an indicator of kidney function (glomerular filtration rate, GFR).

Sequence

SSPGKPPRLVGGPMDASVEEEGVRRALDFAVGEYNKASNDMYHSRALQVVRARKQIVAGVNYFLDVELGRTTCTKTQPNLDNCPFHDQPHLKRKAFCSFQIYAVPWQGTMTLSKSTCQDA

Physical form

Supplied as a lyophilized powder containing tris buffered saline and methionine.

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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