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M5757

Sigma-Aldrich

Maleic acid sodium salt

~99%

Synonym(s):

cis-Butenedioic acid, Toxilic acid

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About This Item

Linear Formula:
C4H3O4Na
CAS Number:
3105-55-3
Molecular Weight:
138.05
EC Number:
221-461-6
MDL number:
MFCD00070246
UNSPSC Code:
12352106
PubChem Substance ID:
24897040
NACRES:
NA.77

assay

~99%

SMILES string

OC(/C=C\C([O-])=O)=O.[Na+]

InChI

1S/C4H4O4.Na/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+1/p-1/b2-1-;

InChI key

VRVKOZSIJXBAJG-ODZAUARKSA-M

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Biochem/physiol Actions

Maleic acid is a component of cosmetics, fragrances and has industrial applications. It is also a potent nephrotoxin and is implicated to induce glycosuria, aminoaciduria and Fanconi syndrome.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Mei-Ling Hou et al.
Molecules (Basel, Switzerland), 21(3), 367-367 (2016-03-22)
Maleic acid has been shown to be used as a food adulterant in the production of modified starch by the Taiwan Food and Drug Administration. Due to the potential toxicity of maleic acid to the kidneys, this study aimed to
Nidambur Vasudev Ballal et al.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 112(5), 696-700 (2011-08-30)
The aim of this study was to evaluate the antimicrobial efficacy of 7% maleic acid (MA) and 17% ethylenediaminetetraacetic acid (EDTA) in elimination of Enterococcus faecalis, Candida albicans, and Staphylococcus aureus at different time intervals. Transfer culture of microbial strains
Ke Chen et al.
Dalton transactions (Cambridge, England : 2003), 41(17), 5391-5400 (2012-04-05)
A series of enantiomerically pure 1,2-diester substituted P,N-ligands incorporating two chiral carbons in the backbone were generated in high yields and high stereoselectivity from acetylenedicarboxylate via initial hydrophosphination using diphenylphosphine followed by hydroamination with various primary and secondary amines. The
Jing-hang Xu et al.
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 20(7), 512-516 (2012-10-10)
To evaluate the efficacy and safety of entecavir (ETV) maleate versus ETV in Chinese patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB). This was a randomized, double-blind, double-dummy, controlled, multicenter study. Patients were randomly assigned to receive
Stéphane Pietravalle et al.
Environmental pollution (Barking, Essex : 1987), 176, 42-47 (2013-02-16)
Multiple substrate induced respiration (MSIR) assays which assess the response of soils to carbon source amendment are effective approaches to determine catabolic diversity of soils. Many assays are based on a single short term (<6 h) time point measurement and
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