LO1280
LOPAC®1280
Synonym(s):
Library of Pharmacologically Active Compounds
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About This Item
UNSPSC Code:
12352202
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General description
Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 μl at 10 mM in DMSO).
Application
LOPAC®1280 has been used:
- in the screening of novel inhibitors for chemotaxis/ migration using Dictyostelium as a model
- to test the ability to modulate and to measure forskolin-stimulated cAMP levels in CHO-hCB2 cells and to modulate ligand-induced receptor/β-arrestin interaction
- in screening of small molecules for activating bone morphogenetic protein (BMP) signaling
- in screening of compounds that plays a role in regulating subcellular localization of nitric oxide associated protein 1 (NOA1) protein
Features and Benefits
Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:
- Apoptosis
- G Proteins & Cyclic Nucleotides
- Gene Regulation & Expression
- Ion Channels
- Lipid Signaling
- Multi-Drug Resistance
- Neurotransmission
- Phosphorylation
SDFile provided to construct a database containing:
- Structure
- Primary Name
- Secondary Name
- Pharmacological Activity
- Product Number
- Rack Position
Collection of 1,280 Pharmacologically-Active Sigma Compounds
To request a list of components, please visit sigma.com/LOPAC
Other Notes
For sale in the U.S. only. Customers outside of the U.S. should refer to product code LO3300.
Legal Information
LOPAC is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Lact. - Muta. 1B - Repr. 1A - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
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