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L7875

Sigma-Aldrich

DL-Leucine

≥99% (HPLC)

Synonym(s):

(±)-Amino-4-methylpentanoic acid

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CO2H
CAS Number:
328-39-2
Molecular Weight:
131.17
Beilstein/REAXYS Number:
636005
EC Number:
206-328-2
MDL number:
MFCD00063087
UNSPSC Code:
12352209
PubChem Substance ID:
24896484
NACRES:
NA.26

product name

DL-Leucine, ≥99% (HPLC)

Quality Level

200

assay

≥99% (HPLC)

form

powder

color

white

mp

293-296 °C (subl.) (lit.)

solubility

1 M HCl: soluble

application(s)

detection
peptide synthesis

SMILES string

CC(C)CC(N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)

InChI key

ROHFNLRQFUQHCH-UHFFFAOYSA-N

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Application

DL-Leucine is a racemic mixture of the D- and L- enantiomers of Leucine. DL-Leucine is used to form benzimidazole and pyrimidine hydroxy azo dyes with various transition metals. DL-Leucine may be used for the evaluation of chiral amino acid separation techniques.

DL-Leucine is used for the following applications:
  • Used as a standard for the measurement of free amino acids
  • Used in the process of tritiated leucine uptake
  • Used in solution preparation (various organics were used in different combinations and concentrations to model complex surface tension effects, DL-Leucine is one of them). It is chosen due to its presence in atmospheric aerosols and ice nucleation activity as well as for its surfactant character

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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H Chang et al.
British journal of haematology, 111(1), 146-156 (2000-11-25)
Transfusion-associated graft-versus-host disease (TA-GVHD) is usually a fatal outcome of blood transfusion therapy, caused by viable leucocytes contained in the donor blood. Most cases of TA-GVHD occur when less than 4-d-old blood is transfused. We therefore examined the molecular changes
Modeling the surface tension of complex, reactive organic-inorganic mixtures.
A. N. Schwier et al.
Atmospheric Chemistry and Physics, 13, 10721-10732 (2013)
L Sallami et al.
Journal of dairy science, 87(6), 1585-1594 (2004-09-30)
The effect of incorporating a highly autolytic strain (Lactobacillus delbrueckii subsp. bulgaricus UL12) a proteolytic strain (Lactobacillus casei subsp. casei L2A), or a nisin Z-producing strain (Lactococcus lactis, subsp. lactis biovar diacetylactis UL719) into Cheddar cheese starter culture (Lactococcus lactis
Masaki Kajimoto et al.
American journal of physiology. Heart and circulatory physiology, 309(7), H1157-H1165 (2015-08-02)
Nutritional energy support during extracorporeal membrane oxygenation (ECMO) should promote successful myocardial adaptation and eventual weaning from the ECMO circuit. Fatty acids (FAs) are a major myocardial energy source, and medium-chain FAs (MCFAs) are easily taken up by cell and
Satinder K Singh et al.
Nature, 448(7156), 952-956 (2007-08-10)
Sodium-coupled transporters are ubiquitous pumps that harness pre-existing sodium gradients to catalyse the thermodynamically unfavourable uptake of essential nutrients, neurotransmitters and inorganic ions across the lipid bilayer. Dysfunction of these integral membrane proteins has been implicated in glucose/galactose malabsorption, congenital
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