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H7752

Sigma-Aldrich

Serotonin creatinine sulfate monohydrate

powder

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Synonym(s):
5-Hydroxytryptamine creatinine sulfate complex, 3-[2-Aminoethyl]-5-hydroxyindole creatinine sulfate complex, 5-HT
Empirical Formula (Hill Notation):
C14H19N5O2 · H2O4S · H2O
CAS Number:
61-47-2
Molecular Weight:
405.43
MDL number:
MFCD00149653
PubChem Substance ID:
24895804
NACRES:
NA.77

form

powder

Quality Level

100

color

white to off-white

solubility

0.1 M HCl: soluble (Solutions should be freshly prepared.)
95% ethanol: very slightly soluble (Solutions should be freshly prepared.)
absolute ethanol: insoluble

storage temp.

2-8°C

SMILES string

O.OS(O)(=O)=O.CN1CC(=O)NC1=N.NCCc2c[nH]c3ccc(O)cc23

InChI

1S/C10H12N2O.C4H7N3O.H2O4S.H2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10;1-7-2-3(8)6-4(7)5;1-5(2,3)4;/h1-2,5-6,12-13H,3-4,11H2;2H2,1H3,(H2,5,6,8);(H2,1,2,3,4);1H2

InChI key

BKCXVJIGPVULPX-UHFFFAOYSA-N

Gene Information

human ... HTR3A(3359)

Application

Serotonin creatinine sulfate monohydrate has been used:
  • to study its effect on the feeding motions in Caenorhabditis elegans
  • to study the chronotropic responses of serotonin (5-HT) in the zebrafish heart
  • to study the effect of serotonin on isthmus peristalsis

Biochem/physiol Actions

Serotonin creatinine sulfate stimulates neuronal production of catecholamine.
Neurotransmitter.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H7752.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361

Precautionary Statements

P281

Hazard Classifications

Repr. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Structure Search

Quotes and Ordering

Bulk Quote-Order Product
Methods for measuring pharyngeal behaviors
WormBook: The Online Review of C. elegans Biology (2005)
Adolfo E Talpalar et al.
Nature, 500(7460), 85-88 (2013-07-03)
All forms of locomotion are repetitive motor activities that require coordinated bilateral activation of muscles. The executive elements of locomotor control are networks of spinal neurons that determine gait pattern through the sequential activation of motor-neuron pools on either side
Serotonin activates overall feeding by activating two separate neural pathways in Caenorhabditis elegans
Song B and Avery L
The Journal of Neuroscience, 32(6), 1920-1931 (2012)
Effect of serotonin on brown adipose tissue and on its sympathetic neurons
Steiner G and Evans S
The American Journal of Physiology, 231(1), 34-39 (1976)
Kerry L Price et al.
ACS chemical neuroscience, 6(7), 1151-1157 (2015-02-05)
Cys-loop receptors are the site of action of many therapeutic drugs. One of these is the smoking cessation agent varenicline, which has its major therapeutic effects at nicotinic acetylcholine (nACh) receptors but also acts at 5-HT3 receptors. Here, we report
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