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EMU040941

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Pla2r1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CGCATTTGCTACCAGTTCAACCTGCTTTCGTCTCTGTCTTGGAACCAGGCCCATTCTTCATGCCTGATGCAAGGAGGTGCTTTGCTAAGTATTGCAGATGAAGATGAAGAAGATTTCATAAGGAAGCACTTGAGCAAGGTAGTCAAGGAAGTGTGGATTGGTTTGAACCAGCTGGATGAGAAGGCTGGCTGGCAGTGGTCTGATGGAACACCACTCAGCTACCTGAACTGGAGCCAAGAGATAACTCCTGGGCCATTTGTTGAGCATCACTGTGGAACCCTGGAGGTTGTTTCAGCTGCCTGGAGGAGCAGGGACTGCGAGTCCACCTTGCCTTATATATGCAAACGGGATCTAAACCACACTGCGCAGGGAATCCTGGAAAAGGACTCCTGGAAATACCATGCCACTCACTGTGATCCTGACTGGACTCCCTTCAATCGTAAATGCTACAAACTTAAGAAAGACAGAAAGAGCTGGCTTGGGGCTCTGCACTCTTGCCAATCGAATGACAGCGTGTTGATGG

Ensembl | mouse accession no.

ENSMUSG00000054580

NCBI accession no.

NP_032893

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... PLA2R1(18779) , Pla2r1(18779)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Yangbin Pan et al.
Scientific reports, 4, 6660-6660 (2014-10-23)
The M-type phospholipase A2 receptor (PLA2R) is expressed in podocytes in human glomeruli. Group IB secretory phospholipase A2 (sPLA2 IB), which is one of the ligands of the PLA2R, is more highly expressed in chronic renal failure patients than in
N D Quach et al.
Molecular pharmaceutics, 11(10), 3443-3451 (2014-09-06)
The M-type phospholipase A2 receptor (PLA2R1) is a member of the C-type lectin superfamily and can internalize secreted phospholipase A2 (sPLA2) via endocytosis in non-cancer cells. sPLA2 itself was recently shown to be overexpressed in prostate tumors and to be

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