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Key Documents

E0518

Sigma-Aldrich

C1 Esterase Inhibitor from human plasma

aqueous solution, ≥95% (SDS-PAGE)

Synonym(s):

Complement C1 esterase inhibitor, Esterase inhibitor C-1 from human plasma

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About This Item

CAS Number:
80295-38-1
MDL number:
MFCD00212908
UNSPSC Code:
12352202
NACRES:
NA.77

biological source

human plasma

Quality Level

200

assay

≥95% (SDS-PAGE)

form

aqueous solution

mol wt

~105 kDa
 ~105 kDa

UniProt accession no.

P05155

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... SERPING1(710)

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Biochem/physiol Actions

Esterase inhibitor C1 is a multifunctional regulator of all major kinin-generating protein cascade systems. It has been a therapeutic tool in the treatment of hereditary angioedema and complement-mediated inflammatory tissue damage such as capillary leak syndrome, septic shock, multiple organ failure, and hyperacute graft rejection.

Physical form

Solution in 20 mM potassium phosphate, pH 7.0, containing 250 mM KCl

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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