MilliporeSigma
All Photos(1)

D0564

Sigma-Aldrich

Diphtheria Toxin from Corynebacterium diphtheriae

lyophilized powder, Product is in unnicked form

Synonym(s):
DTx
MDL number:
NACRES:
NA.77

Quality Level

form

lyophilized powder

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Application

Diphtheria toxin may be used as a toxin element in the construction of immunotoxin for cell specific cytotoxicity. The translocation domain of bacterial toxins with natural endosome escape mechanism has been used in the development of efficient nonviral vectors for applications in gene therapy.

Biochem/physiol Actions

Inhibits protein synthesis by catalyzing ADP-ribosylation of eukaryotic aminoacyltransferase II.

Physical form

Lyophilized powder containing Tris and EDTA.

Reconstitution

Each vial, when reconstituted to 0.5 mL with sterile distilled water, contains ~1 mg of diphtheria toxin in 0.01 M Tris and 0.001 M Na2EDTA, pH 7.5.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 1 Oral

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service