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C8605

Sigma-Aldrich

Dihydroceramide C8

98%, waxy solid

Synonym(s):

D-erythro-N-Octanoyldihydrosphingosine

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About This Item

Empirical Formula (Hill Notation):
C26H53NO3
Molecular Weight:
427.70
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

98%

form

waxy solid

color

white

solubility

ethanol: 10 mg/mL
DMF: 25 mg/mL
DMSO: 5 mg/mL

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC

InChI

1S/C26H53NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h24-25,28-29H,3-23H2,1-2H3,(H,27,30)/t24-,25+/m0/s1

InChI key

LGOFBZUQIUVJFS-LOSJGSFVSA-N

Biochem/physiol Actions

Inactive form of C8 ceramide for use as a negative control.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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Y W Hsu et al.
Journal of immunology (Baltimore, Md. : 1950), 166(9), 5388-5397 (2001-04-21)
The goal of this study was to elucidate whether triggering the sphingomyelin pathway modulates LPS-initiated responses. For this purpose we investigated the effects of N-acetylsphingosine (C(2)-ceramide) on LPS-induced production of NO and PGE(2) in murine RAW 264.7 macrophages and explored

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